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Characterization of porphobilinogen deaminase mutants reveals that arginine-173 is crucial for polypyrrole elongation mechanism

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Summary: Porphobilinogen deaminase (PBGD). the third enzyme in the heme biosynthesis. catalyzes the sequential coupling of four porphobilinogen (PBG) molecules into a heme precursor. Mutations in PBGD are associated with acute intermittent porphyria (AIP). https://parisnaturalfoodes.shop/product-category/amino-energy-watermelon/
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